the structure of teicoplanin

Actually,teicoplanin is a mixture of several compounds, five major and four minor. All teicoplanins share a same glycopeptide core, termed teicoplanin A3-1 — a fused ring structure to which two carbohydrates are attached. The major and minor components also involve a third carbohydrate moiety — β-D-glucosamine — and differ only by the length and conformation of a side-chain attached to it.

Teicoplanin makes up of a group of five structures which possess a common aglycone, or core, consisting of seven amino acids which are bound by peptide and ether bonds to form a four ring system. These five structures differ by the identity of the fatty acyl side-chain attached to the sugar. The origin of these seven amino acids in the biosynthesis of teicoplanin was studied by 1H and 13C NMR. In particular, teicoplanin contains 4-hydroxyphenylglycine and 3,5-dihydroxyphenylglycine residues, a chlorine atom attached on each of the tyrosine residues, and three sugar moieties, N-fatty acyl-β-D-glucosamine, N-acetyl-β-D-glucosamine, and D-mannose.

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the description of Atovaquone

Atovaquone a chemical compound  belongs to the class of naphthalenes. Atovaquone is a hydroxy-1,4-naphthoquinone, an analog of ubiquinone, with antipneumocystic activity. Atovaquone is manufactured in the US in the liquid form, or oral suspension.

Atovaquone is available as a combination preparation with proguanil that has been commercially available from GlaxoSmithKline since 2000 as Malarone for the treatment and prevention of malaria.

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What can Uracil do?

Uracil, in addition to U G, C, and is one of the four bases of the nucleic acid RNA is represented by the character that is adenine, cytosine, guanine and. In RNA, uracil (U) is coupled to the () adenine via two hydrogen bonds. To DNA, the base uracil is replaced with thymine. Uracil, it is possible for drug delivery and, to use as a medicament. When elemental fluorine is reacted with uracil, 5 - fluorouracil will be generated. 5 - fluorouracil, an anticancer agent to be used to masquerade as uracil during the replication process of the nucleic acid is (antimetabolites). 5 - It is similar in shape to fluorouracil, does not do the same chemical reaction and uracil, RNA synthesis by drugs to eliminate it, to stop the proliferation of cancer cells, inhibits the enzyme replication of RNA.
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Information related with Pantoprazole sodium

Pantoprazole is a proton pump inhibitor drug that inhibits the secretion of stomach acid.
Pantoprazole is created for the short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal reflux disease. Initial treatment is usually eight weeks duration, after which, another eight weeks course of treatment should be considered if this is necessary. It can be used as maintenance therapy for long-term use after the initial response is achieved.
This medication may be the results of certain lab tests, such as drug screenings (pantoprazole can cause a false positive result for THC, the psychoactive ingredient of cannabis.

Pantoprazole sodium is white or almost white crystalline power.It is used for gastric and duodenal ulcers.
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The knowledge of Sirolimus

Sirolimus (INN/USAN), also known as rapamycin, is an immunosuppressant drug used to prevent rejection in organ transplantation; it is especially useful in kidney transplants. It prevents activation of T cells and B-cells by inhibiting their response to interleukin-2 (IL-2). A macrolide, sirolimus was first discovered as a product of the bacterium Streptomyces hygroscopicus in a soil sample from Easter Island — an island also known as Rapa Nui, hence the name. It is marketed under the trade name Rapamune by Wyeth. Sirolimus was originally developed as an antifungal agent. However, this use was abandoned when it was discovered to have potent immunosuppressive and antiproliferative properties. It has since been shown to prolong the life of mice and might also be useful in the treatment of certain cancers. Studies in vitro in mice and in humans suggest sirolimus inhibits HIV replication through different mechanisms, including downregulation of the coreceptor CCR5 and the inhibition of the induction of autophagy. Sirolimus has also been used in preliminary research to combat progeria, a rare disorder that causes individuals to age at an exceedingly rapid pace, leading to death in the early teenage years due to causes such as heart disease or stroke.
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The knowledge of Pramipexole dihydrochloride monohydrate

Pramipexole dihydrochloride monohydrate is a generic drug name.Pramipexole dihydrochloride monohydrate is a white to off-white powder substance. Melting starts above 280 ° C under decomposition. Pramipexole dihydrochloride monohydrate more than 20% soluble in water, about 8% methanol, about 0.5% in ethanol and practically insoluble in dichloromethane.
Pramipexole rapidly absorbed and achieves concentrations in about 2 hours. The absolute bioavailability of pramipexole is more than 90%, indicating that it is well absorbed and undergoes little presystemic metabolism. Food does not affect the extent of pramipexole absorption, although the time of maximum plasma concentration (Tmax) is increased by about 1 hour when the drug is taken with a meal.
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Where to buy Glycoderm (P)

Glycoderm (P) helps to restore a damaged lipid barrier and supplies the skin with Natural Moisturizing Factors (NMF).

Glycoderm (P) is a polyvalent, strongly effective moisturizer with a liposomal structure. The plant-derived liposomal bilayers entrap biotechnologically produced hyaluronic acid and natural blossom honey.

INCI-Name: Water, Honey, Phospholipids, Sphingolipids, Hyaluronic Acid
pH range: 3.0–10.0
Dosage: 3.0–5.0%
Solubility: water-soluble
Preservation: Preserved with phenoxyethanol and dehydracetic acid (Na salt).

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Important informations about MPC– Milk Peptide Complex

MPC-Milk Peptide Complex is used for regenerative care of mature skin. MPC– Milk Peptide Complex reduces the visible signs of aging by inducing the production of extracellular matrix molecules in the dermis, such as collagen type 1, making the skin firmer and improving its elasticity. In addition, MPC– Milk Peptide Complex reduces the wrinkle depth and enhances the overall structure of the skin.

MPC– Milk Peptide Complex contains a complex of activated natural signaling molecules derived from milk, such as TGF-β.
INCI-Name: Whey Protein
pH range: 6.0–7.0
Dosage: 0.5%
Solubility: water-soluble
Preservation: The product is unpreserved.
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Health Benefits of Tinogard TT

Tinogard TT is a sterically hindered phenolic antioxidant, and is a highly effective, non-discoloring stabilizer to prevent deterioration of ingredients sensitive to oxidation, such as perfumes, natural oils, fatty acids and the like. It protects rinse-off products as well as leave on formulations efficiently against thermo-oxidative degradation (e.g. rancidification and color changes).

TINOGARD TT is sterically hindered phenolic antioxidants that, dues to their unique molecular design, is non-volatile and provide non-yellowing performance in oil- and fat-based formulations.It is soluble in most oils, fatty acids and fragrances, thus it can be used in oil based formulations to prevent discoloration and fragrance deterioration.

Uses:

Efficient oil-soluble antioxidants.To overcome shortcomings that gradually change color between the BHT, BHA paste. It is a new type of anti-oxidants.

Personal Care Products:

·Body Wash & Shower products
·Bar Soaps
·Shampoos and Hair Care
·Color Cosmetics
·Deodorants
·Skin Creams & Lotions
·Mouthwash & Toothpaste
·Perfumes/Fragrances/Colognes

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Where to buy Ascorbyl Glucoside(AAG)

Ascorbyl Glucoside(AAG) has a structure in which the C2-hydroxyl group of L-ascorbic acid is masked with glucose. Once selectively permeated through the skin, ascorbyl glucoside is broken down into L-ascorbic acid and glucose by the enzyme alpha-glucosidase.

Because ascorbyl glucoside is broken down into L-ascorbic acid, it has the same functions as L-ascorbic acid: exhibiting high antioxidant activity, acting as a coenzyme for enzymes involved in collagen synthesis (namely prolyl and lysyl hydroxylase), and inhibiting the synthesis of melanin.

Ascorbyl Glucoside(AAG) is a new type of stable vitamin C derived compound.It used in many cosmetic skin-lightening formulations and for the Department of Health announced one of the effective whitening ingredients.

Uses:

ASCORBYL GLUCOSIDE has reported used in the following product types: facial moisturizer/treatment; other products with spf; facial cleanser; anti-aging; sunscreen spf 15 and above; foundation; moisturizer; lip balm; around-eye cream; exfoliant/scrub.

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